Abstract
Thromboxane B2, the stable end product of thromboxane A2, was measured by a sensitive radioimmunoassay in gingival tissue obtained from clinically normal beagle dogs and beagle dogs with gingivitis and periodontitis. The animals with gingivitis contained gingival thromboxane B2 levels nearly twice that of clinically normal gingiva, while animals with periodontitis revealed gingival levels of thromboxane B2 that were 3–1/2 times greater than clinically normal and twice that of dogs with gingivitis.
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