Elevated serum levels of TARC/CCL17, eotaxin-3/CCL26 and vascular endothelial growth factor in a patient with non-episodic angioedema associated with eosinophilia and granulomatous cutaneous reaction

Abstract

Episodic angioedema associated with eosinophilia (EAE) is characterized by recurrent episodes of edema, eosinophilia in peripheral blood, urticaria, fever, and weight gain [1]. Non-episodic angioedema associated with eosinophilia (NEAE) has been reported as a single episode of angioedema that was responsive to treatment of low-dose corticosteroids or antihistamines [2].A 41-year-old Japanese woman noted urticaria and swelling in both lower legs in September 2011. The swelling extended to hands and [...]