Abstract
Nucleoside excretion was monitored in the urine of patients with nasopharyngeal carcinoma, a difficult malignant disease to diagnose at early stages. Separation and quantitation of nucleosides were accomplished by using high performance liquid chromatography. Significantly elevated nucleoside levels were found for patients with newly diagnosed and recurrent carcinomas. The magnitude and timing of the increases indicate the value of monitoring these levels for diagnostic/prognostic evaluations for nasopharyngeal carcinoma.
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