Abstract
Mitochondrial DNA content (MC) is thought to reflect metabolism in developing embryos. MC has been studied as a potential biomarker for embryo quality. Limited data suggests that increased MC is associated with older age, aneuploidy and decreased implantation rates in euploid embryos. We sought to investigate MC in conjunction with time-lapse morphokinetics (TLM) to see if TLM could provide insight on how MC is distributed over time in embryos. In this study, we describe the change in MC between day 3 and day 6, and its relationship with chromosomal status.
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