Abstract

Isolated elevations in midtrimester maternal serum human chorionic gonadotropin concentrations (MShCG) have been reported to be associated with a substantially increased likelihood of fetal congenital malformations (Fejgin et al., 1997). Malformations included a wide range of organ systems, originating at different embryologic developmental stages. We investigated the significance of an isolated elevated MShCG (>2.5 MoM) for the detection of fetal structural anomalies.

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