Abstract
The level of the 90 kD heat shock protein (hsp90) has been shown to be elevated in the peripheral blood mononuclear cells of a subset of SLE patients. We show that this increased level of hsp90 is primarily dependent upon the enhanced transcription of the hsp90 beta gene which is observed in these patients but not in normal controls or SLE patients without elevated protein levels. Elevated transcription of the hsp90 beta gene in SLE patients is not in general paralleled by enhanced transcription of the hsp70 or ubiquitin genes indicating that the hsp90 beta gene is specifically activated in some SLE patients.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
