Abstract
Infantile hemangioma (IH) is one of the most common soft-tissue neoplasms of infancy. Although clinical diagnosis for IH is well-established, the haematological parameters associated with IH are not well explored. In this short study, we observed significantly higher eosinophil (EO) numbers in IH patient blood compared to healthy controls. This contributed to the observed higher EO % in the peripheral blood of IH patients and was irrespective of age. This new haematological finding could carry a potential diagnostic/prognostic relevance for IH.
Highlights
Infantile hemangioma (IH) is a common benign tumour in children that presents as precursor vascular lesions, which either present at birth or develop during the early neonatal period and undergo rapid proliferation[1]
We report significantly elevated eosinophil numbers in Chinese IH patients
We observed a high elevation of EO numbers in IH patients compared to healthy subjects
Summary
Infantile hemangioma (IH) is a common benign tumour in children that presents as precursor vascular lesions, which either present at birth or develop during the early neonatal period and undergo rapid proliferation[1]. Clinical diagnosis for IH is well-established, other than the proposed embryonic stem cell origins of IH5, little is known about the peripheral blood cell repertoire in IH patients, let alone in Chinese patients. This concise study seeks to determine any potential haematological signature(s) that may be present in the peripheral blood of IH diagnosed Chinese patients. We report significantly elevated eosinophil numbers in Chinese IH patients
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