Elevated blood monocyte counts in alcohol-associated hepatitis.

Abstract

In this retrospective study of 164 patients with alcohol-associated hepatitis, we find that the mean absolute monocyte count is 0.95 thousand cells/L, which is significantly higher than the upper limit of normal (0.80 thousand cells/μL) (P < 0.0001). Monocyte count is correlated with disease severity as measured by MELD score (R=0.400, P < 0.0001) and Maddrey discriminant function (R=0.330, P < 0.0001).