Abstract
1basic premises of cancer screening research are disregarded. They selected a group of women screened between 2003 and 2007, who were at increased risk of dying from breast cancer because of their family history, and compared them with another group at increased risk, selected from the unscreened group in the UK Age Trial during 1991–99. They used tumour characteristics to predict 10-year survival (which they converted to 10-year mortality). The compared groups diff er greatly, and how Duff y and co-workers tried to make them comparable is unclear. Some of the detailed inclusion and exclusion criteria that applied to the screened group, such as family history, were largely unavailable for the UK Age Trial, the age-groups studied diff ered, and the women were screened for only 4 years, whereas the cancers in the UK Age Trial were identifi ed over 8 years. Duff y and co-workers conceal
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