Abstract
A direct injection nebulizer (DIN) is used with packed microcolumns for anion chromatography (AC) and size exclusion chromatography (SEC). Two Se species (SeO[sub 3][sup 2[minus]] and SeO[sub 4][sup 2[minus]]) are separated by AC with detection limits of 15 pg of Se. The isotope ratio [sup 74]Se/[sup 78]Se can be measured with a relative standard deviation of 0.5% on 25 ng of each Se species during the actual chromatographic separation. Proteins in human serum are separated by SEC without sample pretreatment. The metals present in each molecular weight fraction are determined by ICP-MS with detection limits of 0.5-3 pg of metal. These absolute detection limits are 1-2 orders of magnitude better than those obtained with conventional nebulizers. 56 refs., 3 figs., 7 tabs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
