Abstract
1,3-Dithiolanes, prepared from diaryl ketones, react with elemental fluorine–iodine mixtures to give the corresponding difluoromethylene derivatives. Under the same conditions, thioglycosides give glycosyl fluorides in good yields. Reaction of 1,3-dithiolanes with fluorine in aqueous acetonitrile provides a remarkably mild method for efficient deprotection to the parent ketone.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have