Abstract

Electrode-assisted fermentation is a new strategy in anaerobic biotechnology. It can be used for reactions in which the average oxidation state of the end product is higher than the substrate. Here we show two applications of an electrode-assisted fermentation for the anoxic production of acetoin. The presented approaches in Shewanella oneidensis and Escherichia coli utilize engineered metabolisms to achieve high product yields of roughly 80 percent under strictly anoxic conditions.

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