Abstract

COVID-19 virus has positive electrical charges. So, particles that are negatively charged would, by opposite charges-electrostatic attraction, inhibit its replication’s first stage (attachment to cells) and mop its extra-cellular particles. Positively charged particles would similarly mop/destroy cells it infects because unlike healthy cells which are neutral, infected/tumor cells have negative electrical charges. Nanoparticles (0.96 nm) of Aluminum-magnesium silicate (AMS), WHO-approved medicine/adjuvant have both negative and positive charged ends. As adjuvant it improves antimicrobials’ efficacies (clearing secondary infections) while as silicate it enhances immunity. By inhibiting viral replication; mopping extra-cellular viruses/abnormal cells; clearing secondary infections; enhancing immunity, AMS terminates viral-infections/abnormal cells’ metastases. Natural AMS has impurities and its deposits are not found in Nigeria. So, Aluminum silicate and Magnesium silicate (WHO-approved medicines) were used for Medicinal synthetic AMS {MSAMS: Al4 (SiO4)3 + 3Mg2SiO4 → 2Al2Mg3 (SiO4)3}. Since AMS is un-absorbable, dextrose monohydrate is incorporated in MSAMS-formulations to convey its Nanoparticles into blood for circulation to all organs/tissues (active-transportation). The MSAMS achieved quick cure (within 3 days) of all four COVID-19 patients used for its first-phase trial (one in Nigeria, two in Cameroon, one in Tanzania).

Highlights

  • Viral pandemics cause global panic because designing medicines to combine curative antiviral efficacies with tolerable side effects is difficult

  • In one of the trials of the MSAMS on HIV/AIDS [13], it took 20 months for the patient to test HIV-negative while in this trial all the COVID-19 patients recovered within 3 days

  • Even the suspected case may have been COVID-19 positive but returned negative because of the single dose of the MSAMS he took before the test, done to confirm diagnosis of COVID-19

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Summary

Introduction

Viral pandemics cause global panic because designing medicines to combine curative antiviral efficacies with tolerable side effects is difficult. Medicines designed to inhibit physical features/physical activities of viruses require complementation from immunity. Otherwise, they cannot terminate viral infections to achieve permanent cure. Antiviral medicines should be designed to inhibit physical features or physical activities of viruses, not their biochemistry (to minimize their side effects). Active principles of such antiviral medicines should be smaller (

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