Electrospray ionization mass spectra of derivatives of 2-phenylthio-N-trifluoroacetylneuraminic acid

Abstract

Regularities in fragmentation of adduct ions [M + NH4]+ and [M + Na]+ of N-trifluoroacetyl neuraminic acid phenyl thioglycosides under collisionally-induced decay (CID) activation are studied. For [M + Na]+ ions, elimination of the C8H8O2S fragment (along with thiophenol molecule) proceeds both in the presence or the absence of an acetyl group, whereas for the [M + NH4]+ ion, elimination of thiophenol C6H6S is observed. Similar elimination of the C8H8O2S fragment has been observed previously only for cationized molecules of phenylthioglycoside acetates of hexoses.