Abstract
Porphyrin 5,10,15,20-Tetra(4-pyridyl)manganese(III), [Mn-TPyP(H2O)2]PF6, and electropolymerized supramolecular porphyrins (ESP), {Mn-TPyP(H2O)2[RuCl3(dppb)]4}PF6 (dppb = 1,4-bis(diphenilphosphine)butane), were synthesized and characterized. A thin solid film of ESP was obtained on a glass carbon electrode surface by a cyclic voltammetry method. The peak current increased with the number of voltammetric cycles, which shows a typical behavior of the species being adsorbed on the surface of the electrode. Cyclic voltammetry was also employed for acetaminophen quantification using an ESP modified electrode. The modified electrode shows a linear relationship between the anodic peak current and the concentration of acetaminophen (in the rage 0.05 to 0.7 mmol L - 1). The performance of the modified electrode was verified by the determination of acetaminophen in a commercial pharmaceutical product and the results were in good agreement with those obtained by a control HPLC method.
Highlights
The importance of porphyrins is not limited to their participation in the transport of oxygen to heme proteins and photosynthetic activities
The results showed that anodic peak currents change linearly with the square root of the scan rate (ν1/2) for acetaminophen which indicates a diffusioncontrolled process for electrooxidation of acetaminophen on the surface of the EPSE according to the following equation:[52]
This work reports on the synthesis and characterization of a new supramolecule containing manganese (III) and peripheral ruthenium (III) complexes {Mn‐TPyP(H2O)2[RuCl3(dppb)]4}PF6
Summary
The importance of porphyrins is not limited to their participation in the transport of oxygen to heme proteins and photosynthetic activities. They have valuable contributions in various fields, such as liquid crystalline materials,[1] due to their remarkable electrooptical properties, oxygen measurements in vivo,[2,3] photodynamic therapy,[4,5] malaria treatment,[6] molecular. Determination using electrochemical techniques has been demonstrated to be promising.[27,28,29,30,31,32,33,34] One of the first studies reported the use of glassy carbon electrodes modified with 4-vinylpyridine.[35] Shortly after, the electropolymerized porphyrin was already being used as the modified electrode for the determination of acetaminophen.[36]
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