Electrophysiological Studies Do Predict Sudden Cardiac Arrest in Brugada Syndrome

Abstract

Some patients with Brugada syndrome are at risk for sudden cardiac arrest (SCA), but predicting who possesses a malignant phenotype is difficult. Surely, patients with resuscitated SCA are at risk for future events. Syncope that appears arrhythmic also likely predicts future SCA. The use of programmed electrical stimulation (PES) is controversial, although the Brugada brothers, who first described the syndrome, have long argued that PES induction of ventricular fibrillation is predictive …