Abstract
The standing potential (SP) of the eye is generated mainly at the apical surface of the pigment epithelium, where tight junctions between adjacent cells create a high resistance membrane. It can be recorded indirectly by means of the electrooculogram (EOG) or directly by recording between electrodes connected to the cornea and the forehead. Changes in illumination provoke slow SP changes in the form of damped oscillations with a frequency of about 2/hour. These oscillations are abolished or substantially reduced in pigment epithelial diseases, such as retinitis pigmentosa and vitelline macular degeneration.
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