Abstract
This double-blind investigation compared the effects of doxepin, hydroxyzine HCl, and placebo on muscle action potentials (MAPs) and skin conductance (GSR) parameters as functions of experiencing either success or failure in concept-identification performance of 30 psychiatric anxiety patients. Results showed the following: (1) increase in MAPs with failure, (2) reduction of MAPs by both medications, (3) a greater number of spontaneous GSRs in the success condition compared with the failure condition, and (4) a significant negative relationship between MAPs and GSRs.
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