Electrophysiological changes elicited by auditory stimuli given a positive or negative value: a study comparing anhedonic with hedonic subjects

Abstract

The present experiment investigates in ‘normal’ subjects the relationship between personality characteristics (anhedonia versus hedonia) and the influence of the affective value of acoustic stimuli (positive, negative, neutral) on various electrophysiolgocical indices reflecting either tonic activation or phasic arousal (EEG power spectra, contingent negative variation: CNV, heart rate, skin potential responses: SPR) as well as on behavioural indices (reaction time: RT). Eighteen subjects were divided into two groups according to their scores at two self-rating questionnaires, the Chapman's Physical Anhedonia Scale (PAS) and the Beck-Weissman's Dysfunctional Attitude Scale (DAS) that quantifies cognitive distortions presumed to constitute high risk for depression: 9 with high scores at both scales formed the A group (Anhedonic-dysfunctional), 9 with low scores at both scales, the H group (Hedonic-adapted) The electrophysiological indices were recorded during 3 situations: the first one was a classical CNV paradigm with a motor reaction time task in which one of 3 tones of different pitch represented the warning stimulus S1; during the second, conditioning phase, two of these tones were associated with either a success (and reward) or a failure (and punishment) during a memory task in order to make them acquire either a positive or a negative affective value; the third situation consisted in the repeating of the first CNV paradigm in order to test the effect of the positive and the negative stimuli versus the neutral one on RTs and electrophysiological data. Significant between-group differences were found regarding tonic activation as well as phasic arousal indices from the very beginning of the experiment when all stimuli were neutral ones, the anhedonics exhibiting higher activation and arousal than the hedonics at the cortical (increased CNV amplitude, increased power in the beta frequency band), cardiovascular (higher heart rate habituating more slowly) and behavioural (faster RTs) levels. Significant between-group differences were also found concerning reactivity to affective stimuli during the third situation: both the orienting response (but only at the cortical level: early CNV) and the motor preparation processes (late CNV) were in the A group significantly less reactive to affective stimuli (especially to the positive one) than in the H group, in particular concerning the frontal (Fz) data.