Abstract

1. 1. An electrophoretic study of carbonylhemoglobin derived from cord blood obtained from full-term and premature live human infants from 16 to 48 weeks postconception has shown definitely that a form of hemoglobin is present in the red cells of these infants that differs from normal adult human hemoglobin. 2. 2. Human fetal hemoglobin for the age group between 32 and 48 weeks has an electrophoretic mobility ranging from +0.10 to +0.00 in the pH range 6.94 – 7.00, in potassium phosphate buffer of 0.1 ionic strength. 3. 3. Human fetal hemoglobin differs from human adult hemoglobin also in the effect on electrophoretic mobility of change from carbonylhemoglobin to ferrohemoglobin, the effect on electrophoretic mobility of change in buffer ions, the effect of caprylate ion in producing a colorless constituent, and the number of components of the globin obtained on removal of the heme by acid treatment.

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