Abstract

New electrophilic fluorination reagent HF·THF/PhIO was introduced and tested on three general classes of compounds. Compared with the literature data reported for basic reagents, such as HF/TEA/PhIO and HF/Py/PhIO, the new reagent showed superior performance in fluorination of aromatic alkenes, subpar reactivity with ketones and malonates, while in the reactions with 1,3-unsaturated carbonyl compounds the results were much the same as the literature data.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call