Abstract

Electrophilic cyclization of <i>N</i>-(3-arylprop-2-ynyl)amides to functionalized 4<i>H</i>-1,3-oxazines is described. It was found that the presence of an electron-rich aryl group next to the triple bond is crucial for a smooth and highly regioselective 6-<i>endo</i>-dig ring closure process.

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