Abstract
The development of transplants of embryonic rabbit retinal tissue to adult rabbit eyes was examined in the electron microscope. Neuroretinas from mid gestational age (E14-E20) were transplanted into ten adult hosts and allowed to develop subretinally in the host eye for one to 13 weeks. The transplanted immature retinal cells continued to develop after transplantation, differentiating into different cell types. They developed several of the normal ultrastructural cell characteristics, which made it possible to identify many of the normal retinal cell types.After one week immature rosettes were seen, with zonulae adherentes between the photoreceptor cells and Muller cells, forming an outer limiting membrane. After five weeks a more mature-like structure was revealed. Photoreceptor cells had developed both inner and outer segments and synaptic terminals. The transplants were heterogeneously developed with some parts showing almost normal differentiation and others little. Incompletely differentiated synapse...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
