Abstract
Young larvae of the honey bee, Apis mellifera, 12–36 hours old were experimentally infected with purified sacbrood virus (SBV). Virus was found in fat, muscle, and tracheal-end cells 48 and 72 hours after initial virus acquisition by larvae. Particles were always found free in the cytoplasm of infected cells and were not associated with any cell organelle. Fibrillar material, most likely nucleic acid, was observed within some virus inclusions.
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