Abstract

We are using electron diffraction to characterize a platinum-containing derivative of bacteriorhodopsin, the light-driven proton pump from Halobacterium halobium. This has been undertaken with the dual aims of: 1)using the method of multiple heavy atom isomorphous replacement to obtain high resolution structural information about the protein, and 2)locating heavy atom labelled amino acids in the structure in order to correlate the recently determined sequence with the structural map. A necessary first step in such studies is the location of the heavy atoms in the low resolution structure. This report focusses on ways of dealing with the inherent statistical uncertainties encountered in this heavy atom localization.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.