Abstract

With the objective of improving MR endoluminal imaging of the colonic wall, electromagnetic simulations of different configurations of single-layer and double-layer, and double-turn endoluminal coil geometries were run. Indeed, during colon navigation, variations in coil orientation with respect to B0 are bound to occur, leading to impaired image acquisition due to a loss of signal uniformity. In this work, three typical coil orientations encountered during navigation were chosen and the resulting signal uniformity of the different geometries was investigated through the simulatedB1x,y/IRtvalues. Sampling this quantity over a circle of radius r enabled us to calculate the coefficient of variation (= standard deviation/mean) for this given distance. This procedure was repeated forr∈5;15 mm, which represents the region of interest in the colon. Our results show that single-loop and double-layer geometries could provide complementary solutions for improved signal uniformity. Finally, using four microelectromechanical system switches, we proposed the design of a reconfigurable endoluminal coil able to switch between those two geometries while also ensuring the active decoupling of the endoluminal coil during the RF transmission of an MR experiment.

Highlights

  • With the objective of improving MR endoluminal imaging of the colonic wall, electromagnetic simulations of different configurations of single-layer and double-layer, and double-turn endoluminal coil geometries were run

  • Our results show that single-loop and double-layer geometries could provide complementary solutions for improved signal uniformity

  • Introduction e main inflammatory bowel diseases are ulcerative colitis and Crohn’s diseases [1]. ey affect the colon and/or rectum with an increased risk to evolve into colorectal cancer (CRC) [2], which is one of the most common cancers [3, 4]

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Summary

Introduction

With the objective of improving MR endoluminal imaging of the colonic wall, electromagnetic simulations of different configurations of single-layer and double-layer, and double-turn endoluminal coil geometries were run. Erefore, it is important to develop new imaging devices or techniques able to provide an accurate diagnosis for each stage, the early stage To this end, magnetic resonance imaging (MRI) is one of the major techniques used for medical diagnosis thanks to several developments to improve significantly the signal-tonoise ratio (SNR) by increasing the static magnetic field strength [8, 9], or increasing the number of receiver channels and using surface arrays coils [10]. Magnetic resonance imaging (MRI) is one of the major techniques used for medical diagnosis thanks to several developments to improve significantly the signal-tonoise ratio (SNR) by increasing the static magnetic field strength [8, 9], or increasing the number of receiver channels and using surface arrays coils [10] All these developments are still insufficient for bowel and colon wall imaging. In the context of colon imaging, endoluminal coils provide a high local SNR very

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