Abstract
The commonly used diagnostic methods for liver malignancies are core needle biopsy (CNB), fine needle aspiration cytology (FNAC), and touch imprint (TIC), but these methods have contradictory and uncertain results. We investigate a plasmon biosensor that uses a hBN ring structure coupled with a silver rectangular square ring to identify healthy cells and metastatic cancer cells in liver cells. We study the influence of the structure's output characteristics and geometric parameters on the plasmon resonance. The results show that the designed structure can achieve refractive index sensitivity up to 920 nm / RIU, and the maximum quality factor is 58RIU-1 when the change of the sensing medium refractive index Δn = 0.4. Our method showed good spectral response to non-cancerous (NMET) and metastatic (MET) cancerous liver tissue cells. The device has broad application prospect in plasma sensing and absorber design.
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