Abstract
The surface potential of a membrane is involved in a number of important physiological processes such as fusion, recognition, and solute binding. Artificial models such as tethered lipid bilayers enable us to capture several key properties of complex biological lipid membranes such as their lateral dynamics, molecular structure, and interactions with peripheral proteins. Membrane electrostatics represents one further aspect for these mimics to address. Here we demonstrate how the surface potential of tethered phospholipid bilayers may be electrokinetically determined with accuracy of a couple mV, by measuring the membrane streaming potential in a well-defined laminar flow.
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