Electrogenerated thianthrenium conjugate enables (Z)-selective allylic amination

Abstract

Developing straightforward methodologies to access allylic amines is of contemporary importance in drug development and natural product synthesis. Recently, Wickens et al<i>.</i> developed an electrochemical approach with thianthrene adducts as reactive functional intermediates to transform terminal olefins and secondary amines into tertiary allylic amines in high yields and distinct <i>Z</i>-selectivity.