Abstract
Elevated EEG alpha activity has been reported to distinguish depressed patients from control subjects, but the hypothesis that such differences characterize depressed patients after clinical recovery has not been systematically assessed. In this study, three groups of elderly volunteers were compared using quantitative EEG indices. One subject group had DSMIII-R diagnoses of Major Depression; a second group had past histories of DSM-III-R Major Depression, but were euthymic at the time of the EEG; and a third group were healthy normal volunteers, without histories of Axis I psychiatric disorder. Significant differences in EEG alpha amplitude distinguished the groups. Subjects who were currently depressed and subjects who had past histories of major depression showed elevated EEG alpha as compared to controls. The state and trait specificity of these findings are discussed.
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