Abstract
THE amphetamine derivative, 2,5-dimethoxy-4-methyl-amphetamine (STP), is a new psychotomimetic drug, considered to be about one hundred times more powerful than mescaline in producing psychedelic symptoms in human beings1. We have made an electroencephalographic (EEG) analysis to determine the sites of action in rabbit brain of d-amphetamine and STP. It has been shown that non-psychotomimetic congeners provoke EEG alerting from the midbrain level, while their psychotomimetic congeners such as LSD, psilocin and mescaline cause alerting by their action at a lower level in the brain-stem2–4.
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