Abstract

One hundred patients with the clinical diagnosis of narcolepsy were examined electroencephalographically. The basal or alert electroencephalograms were found to be within normal limits. Drowsiness beginning within the first 4 min. of the recording occurred in the majority of patients. Almost all patients manifested drowsiness at some time during the recording. Sustained drowsiness lasting for periods up to 30 min. was characteristic of these patients. Opening and closing the eyes, counting, hyperventilation and photic stimulation, measures which alert the normal patient, were commonly ineffective in narcoleptics. In spite of persistent drowsiness, actual sleep was uncommon under the circumstances in which the recordings were made. Electroencephalograms made during cataplectic attacks and an attack of sleep paralysis were normal. The implications of these findings are discussed.

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