Abstract

This study deals with neurophysiologically based models simulating electrical brain activity (i.e., the electroencephalogram or EEG, and evoked potentials or EPs). A previously developed lumped-parameter model of a single cortical column was implemented using a more accurate computational procedure. Anatomically acceptable values for the various model parameters were determined, and a multi-dimensional exploration of the model parameter-space was conducted. It was found that the model could produce a large variety of EEG-like waveforms and rhythms. Coupling two models, with delays in the interconnections to simulate the synaptic connections within and between cortical areas, made it possible to replicate the spatial distribution of alpha and beta activity. EPs were simulated by presenting pulses to the input of the coupled models. In general, the responses were more realistic than those produced using a single model. Our simulations also suggest that the scalp-recorded EP is at least partially due to a phase reordering of the ongoing activity.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.