Abstract

The electrodiagnostic (EDX) examination in patients with suspected neuromuscular junction (NMJ) disorders requires a good comprehension of the physiology and pathophysiology of neuromuscular transmission. The EDX studies that are useful in the evaluation of such patients include: 1) motor nerve conduction studies (NCSs); 2) conventional needle electromyography (EMG); 3) repetitive nerve stimulation (RNS); and 4) single-fiber EMG. This chapter reviews, in brief, basic knowledge of neuromuscular transmission as it relates to the EDX studies and discusses in detail the EDX studies and findings in various NMJ disorders.

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