Abstract

A self-assembled novel nanocomposite composed of MoS2-Graphene(MoS2-Gr) composites were electrostatically formed on top of gold (Au) electrode and their biochemical amplification responses were reported. The properties of the MoS2-Gr were characterized by scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HR-TEM), X-ray diffraction (XRD), and Fourier transform infrared spectrometer (FT-IR). Cyclic voltammetry was performed in the presence of Parathyroid Hormone (PTH) and its linearity was obtained by measuring the anodic current signals coming from interactions between MoS2-Gr-Ab and different concentrations of PTH with the aid of substrate and enzyme conjugated secondary antibodies. With this complex and Au as working electrode, we have developed a portable biosensing platform which shows good sensitivity in detecting PTH as low as 10 pg/mL and high reproducibility

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