Abstract

AbstractA large mesoporous carbon modified glassy carbon electrode (LMC/GCE) was prepared. The morphology and structure of the LMC were characterized. The LMC/GCE was used to investigate the electrochemical behaviors of metabolites of purine nucleotide, uric acid (UA), xanthine (XA) and hypoxanthine (HX). The LMC/GCE exhibited high electrocatalytic activity towards the three compounds when compared with those obtained at the GCE. Furthermore, the LMC/GCE realized simultaneous determination of UA, XA and HX at a physiological pH of 7.0 with wide linear range and low detection limit. The electrocatalytic activity of the LMC/GCE towards guanine (G) and adenine (A) was also investigated.

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