Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture

Abstract

Mg and its composites are considered attractive candidates for supplying biomedical implantation. Mg-alloys are gaining popularity for biomedical implant applications, particularly bone regeneration because they have characteristics that are like those of natural bone. Simulated body fluid (SBF) is an electrolyte that is often utilized in vitro corrosion investigations. Using each SBF module individually and in combination, this research evaluates the corrosion effects on the system. pH alterations hasten the degeneration of the organism's pH and it was decided to explore the corrosion of Mg in an SBF. In this study, the effect of pH changes on the corrosion rate of Mg immersed in standard SBF solution was investigated in detail. According to previously published research, the corrosion process of Mg has been substantiated by scanning electron microscopy examinations of damaged surface morphology. In this investigation, pH 7 was determined to be the optimal pH for physiological fluids since it is neutral. To accomplish these aims, researchers examined Mg–2 wt.% Zn–0.5 wt.% Ca (ZC21) alloy pins microstructurally and mechanically, as well as the degradation of the alloy pins and their interactions with the SBF solution. The degradation of bone and its cytocompatibility with other substances. The degradation control of Mg-alloy occurred at a much slower rate than that of Mg alone. Bone cell development on the applied nano alloy is visible on SEM-EDS charts, demonstrating that this alloy is extremely compatible with human bone and that its usage as a stent for bone fracture is highly suggested in this study.