Abstract
As para-aminophenol (PAP) is toxic to humans, causing skin irritation, eye damage, and central nervous system depression, and it can form as a degradation product of paracetamol (PAT) under certain conditions, the simultaneous determination of PAP and PAT is crucial. This work presents the fabrication of three-dimensional ZnCo2O4@Fe3O4/MWCNTs hybrid for the simultaneous determination of PAP and PAT using ZIF-8/67@Fe3O4 as precursor and MWCNTs as conductive substrate. The ZnCo2O4@Fe3O4/MWCNTs/GCE sensor exhibits linear ranges 1.0–150.0 μM with detection limits of 0.033 μM and 0.018 μM for PAP and PAT, respectively. The developed sensor was successfully used for the determination of PAP and PAT in acetaminophen tablets and lake water with satisfactory results.
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