Abstract

3-Selenyl quinolines are an important class of compounds that have found significant applications in pharmaceuticals and synthetic chemistry. Herein, we describe an electrochemical oxidative selenocyclization under undivided electrolytic conditions, thereby providing an efficient rout to access 3-selenyl quinolines. The merit of this method has been well demonstrated by its green and environmental-friendly conditions, being external oxidant-free, short reaction time, broad substrate scope and ease of scale-up to gram scale.

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