Abstract
Folid acid (FA) undergoes three distinct reduction steps in acidic media and a single reduction step in alkaline media. Analysis of constant potential electrolysis products by high performance liquid chromatography reveals that, in acidic medium, the first reduction step converts FA to a transient 5,8-dihydro-FA, some of which tautomerizes to 7,8-dihydro-FA, while the remainder undergoes a proton dependent non-electrochemical cleavage of the para-aminobenzoylglutamate side chain. Step two involves the electrochemical cleavage of the C (9)N (10) chemical bond of the 7,8-dihydro-FA while the final reduction converts the 6-methyl-7,8-dihydropterin derivative generated in step two to a 6-methyl-5,6,7,8-tetrahydropterin. Above neutrality, only a single 2e −/2H + reduction step is observed because the proton dependent tautomerization process is slow. Differential pulse, normal pulse polarography and cyclic voltammetric results indicate that reduction of FA is subject to considerable adsorption in both the acidic and alkaline media.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
