Abstract

Electrochemical Oxidation of 2’-deoxyguanosine-5’-triphosphate on Ionic Liquid Modified Carbon Paste Microelectrode and its Sensitive Detection

Highlights

  • Electrochemical oxidation of 2’-deoxyguanosine-5’-triphosphate was investigated on the ionic liquid modified carbon paste microelectrode by cyclic voltammetry in this paper

  • Electrochemical behaviors of dGTP on mCILE was investigated by cyclic voltammetry with a series of redox peaks appeared, which was due to the initial oxidation of dGTP to a diimine species with following chemical reaction to give different products

  • Due to the presence of Ionic liquids (ILs) in the electrode, the electrochemical response was increased, which was ascribed to the electrocatalytic ability of mCILE

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Summary

Introduction

Electrochemical oxidation of 2’-deoxyguanosine-5’-triphosphate (dGTP) was investigated on the ionic liquid modified carbon paste microelectrode by cyclic voltammetry in this paper. Xie et al investigated the electrochemical behavior of guanine, guanosine, and guanosine monophosphate at redox polymer film modified indium tin oxide (ITO) electrode.[6] Goyal et al investigated the electrochemical oxidation mechanism of guanosine-5’-triphosphate (GTP)[7] and guanosine-5’-monophosphate[8] at a pyrolytic graphite electrode. Preparation of carbon paste electrodes with ILs as a binder, which is often named as carbon ionic liquid electrode (CILE), has been reported by several groups.[11,12,13,14] ILs-based carbon paste

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