Abstract
AbstractIn this work we used electrochemical methods, open circuit potential (OCP) measurement with platinum electrode, and cyclic voltammetry (CV) in blood serum to assess redox states in patients with polytrauma (n=56) that allow to evaluate probability of survival early on, and therefore have the potential to improve therapy outcomes. Electrochemical assessment of redox states in sera samples correlated with traditional methods of prooxidant/antioxidant balance quantification. OCP and quantity of electricity passed (Q), calculated from CVs, were significantly different between the survivors and non‐survivors. Patients with Q>22 μC (day 1) and OCP>34 mV (day 3) had low chance of survival.
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