Abstract
Objective:A poly niacin (NN) modified graphite paste electrode was prepared through a simple electrochemical polymerization route for the determination of Riboflavin (RF)Methods:Electropolymerization technique was used for the preparation of a modified electrode. The electrochemical impedance spectroscopy (EIS) method was used to study the surface behaviors and conductivity of the bare and modified electrodes. Cyclic voltammetry (CV) and linear sweep voltammetry (LSV) were used to study the electrochemical behavior of RF using 0.2 M PBS of 7.5 pH.Results:Poly niacin modified graphite paste electrode (PNNMGPE) provides more affinity towards RF detection with high sensitivity and selectivity over bare graphite paste electrode. RF calibration curve was obtained by LSV between 5.0 µM to 65.0 µM with 0.782 µM limit of detection (LOD) and 2.7608 µM limit of quantification (LOQ), respectively. Selective analysis of RF in the presence of ascorbic acid (AA) and dopamine (DA) was performed at PNNMGPE by the LSV method.Conclusion:The developed PNNMGPE was tested for RF analysis in a multivitamin tablet with good results. Furthermore, the developed electrode shows good stability and reproducibility.
Highlights
Riboflavin (RF) or vitamin B2 is used as a dietary supplement and it is a water-soluble B group vitamin, and a a constituent of flavoenzymes [1, 2]
Different modified electrodes using amino acids, dyes, nucleotides, neurotransmitters, phenolic compounds, metal nanoparticles, metal complexes, clay, ionic liquids, surfactants, metal oxides, enzymes and DNA modified sensors etc., with different functional groups are widely reported for determination of electroactive species due to their stability, electrocatalytic performance, biocompatibility, antifouling properties, and high applicability [33 - 44]
Modified electrode controls over potential and improves the sensitivity of sensors. Carbon materials such as graphite, carbon nanotube, graphene, pencil graphite, glassy carbon, activated carbon, and biomass carbon are the best choices for the fabrication of sensors and supercapacitors due to their extensive potential domains, chemical inertness, low ohmic resistance, robustness, mechanical stability, excellent material characteristics, provides lower detection limits with reproducible responses, high surface area, good thermal and electrical conductivity, good anti-causticity, high stability, low cost and commercial-scale availability [45 - 57]
Summary
Riboflavin (RF) or vitamin B2 is used as a dietary supplement and it is a water-soluble B group vitamin, and a a constituent of flavoenzymes [1, 2] It plays an important role in human biochemistry and metabolism. Modified electrode controls over potential and improves the sensitivity of sensors Carbon materials such as graphite, carbon nanotube, graphene, pencil graphite, glassy carbon, activated carbon, and biomass carbon are the best choices for the fabrication of sensors and supercapacitors due to their extensive potential domains, chemical inertness, low ohmic resistance, robustness, mechanical stability, excellent material characteristics, provides lower detection limits with reproducible responses, high surface area, good thermal and electrical conductivity, good anti-causticity, high stability, low cost and commercial-scale availability [45 - 57]. The present effort describes RF quantification and detection at PNNMGPE using the voltammetry technique
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