Electrochemical determination of paracetamol, rutin and sulfonamide in pharmaceutical formulations by using glassy carbon electrode – A Review

Adane Kassa,Meareg Amare,Refaat Mohamed Mahfouz

doi:10.1080/23312009.2019.1681607

Adane Kassa, Meareg Amare + Show 1 more

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https://doi.org/10.1080/23312009.2019.1681607

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Journal: Cogent Chemistry	Publication Date: Jan 1, 2019
Citations: 17	License type: CC BY 4.0

Affiliation: Bahir Dar University

Abstract

Recent advances in the electrochemical application of glassy carbon electrode for determination of selected drugs in pharmaceutical formulations are reviewed. Several analytical techniques such as ...

Highlights

The drug development process starts with the foundation of a drug molecule that has shown therapeutic value to battle, control, and check or cure diseases
The synthesis and characterization of such molecules which are called active pharmaceutical ingredients (APIs) and their analysis was done for a long time by different analytical methods to examine their safety use and therapeutic efficacy of drug (Masoom et al, 2017; Nineza, 2010)
High-performance liquid chromatography, spectrophotometry, chemiluminescence, and capillary electrophoresis-mass spectrometry are the conventional methods reported for the determination of pharmaceutical active components due to their high sensitivity and great selectivity (De-Abreu et al, 2003; Deng et al, 2008; Ge et al, 2013; Laina & Girish, 2013; Qader & Fakhre, 2017)

Summary

Introduction

The drug development process starts with the foundation of a drug molecule that has shown therapeutic value to battle, control, and check or cure diseases. The instrumental methods used for quantization of the drugs are most commonly divided into four basic categories: chromatographic, spectrophotometric, electrochemical, and radiometric analysis (Nineza, 2010) From this liquid chromatography, high-performance liquid chromatography, spectrophotometry, chemiluminescence, and capillary electrophoresis-mass spectrometry are the conventional methods reported for the determination of pharmaceutical active components due to their high sensitivity and great selectivity (De-Abreu et al, 2003; Deng et al, 2008; Ge et al, 2013; Laina & Girish, 2013; Qader & Fakhre, 2017). On the contrary electrochemical methods overcome those drawbacks owing to its low cost, rapid response and application in the on-site test (Hassaninejad & Shajie, 2017; He & Yan, 2017)

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