Abstract

ABSTRACT The electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a linear detection range of 1–80 µM for glutathione with a corresponding limit of detection of 0.94 µM. The efficacy of the approach has been shown by the 104% (RSD = 7.3%, N = 3) recovery of 10 µM glutathione in a growth tissue media containing a number of important biomarkers.

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