Electrochemical Deposition of Silver—Gold Nanoparticles for Sensitive Dopamine Detection

Abstract

first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessAbstract Electrochemical Deposition of Silver—Gold Nanoparticles for Sensitive Dopamine Detection † by Irina-Alexandra Crudu, Adina Arvinte * and Mariana Pinteala “Petru Poni” Institute of Macromolecular Chemistry, 700487 Iasi, Romania * Author to whom correspondence should be addressed. † Presented at the 5th International Symposium on Sensor Science (I3S 2017), Barcelona, Spain, 27–29 September 2017. Proceedings 2017, 1(8), 704; https://doi.org/10.3390/proceedings1080704 Published: 11 December 2017 (This article belongs to the Proceedings of Proceedings of the 5th International Symposium on Sensor Science (I3S 2017)) Download Download PDF Download PDF with Cover Download XML Versions Notes * Correpondence: [email protected]Dopamine (DA) is a catecholamine neurotransmitter, which plays a crucial role as chemical messengers in the central nervous system, hormonal, cardiovascular and renal systems. Recently, much attention has been paid to trace level determination of DA, because small changes in concentration are coupled with various disorders such as Alzheimer’s disease, epilepsy, Parkinson’s disease and schizophrenia [1]. In this context, the selective and sensitive approach for DA level determination is vital for diagnosing diseases.Due to its electroactivity, DA can be detected by electrochemical techniques, but requires large oxidation potential, which results in the formation of phenoxy radicals and, respectively, formation of polymeric films on the electrode, passivating the surface. It has been shown that metal nanoparticles in combination with carbon material can enhance the sensing activity of electrodes for dopamine oxidation [1,2,3]. Carbon nanotubes (CNTs) decorated with different metallic nanoparticles have been frequently used to modify the surfaces of commercially available screen-printed electrodes to decrease the overpotential and improve sensitivity.This work demonstrates the effective surface electrodeposition of bimetallic Ag-Au nanoparticles onto CNTs substrate for sensitive and selective detection of dopamine. The double-pulse amperometry method has been used for Ag-Au deposition, with different deposition parameters such as pulse time, metal ions ratio and total time of deposition. Scanning electron microscopy was used for morphologic characterization of deposited nanoparticles, while cyclic voltammetry and differential pulse voltammetry were involved in the electrochemical characterization of the sensors towards dopamine detection. AcknowledgmentsRomanian National Authority for Scientific Research and Innovation, CNCS/CCCDI—UEFISCDI, project number PN-III-P3-3.6-H2020-2016-0011.Conflicts of InterestThe authors declare no conflict of interest.ReferencesIswarya, C.N.; Kiruba Daniel, S.C.G.; Sivakumar, M. , Studies on l-histidine capped Ag and Au nanoparticles for dopamine detection, Mater. Sci. Eng. C 2017, 75, 393–401. [Google Scholar] [CrossRef] [PubMed]Jackowska, K.; Krynsinski, P. , New trends in the electrochemical sensing of dopamine, Anal. Bioanal. Chem. 2013, 405, 3753–3771. [Google Scholar] [CrossRef]Fayemi, O.E.; Adekunle, A.S.; Ebenso, E.E. , Metal Oxide Nanoparticles/Multi-walled Carbon Nanotube Nanocomposite Modified Electrode for the Detection of Dopamine: Comparative Electrochemical Study. J. Biosens. Bioelectron. 2015, 6, 190–204. [Google Scholar] [CrossRef]Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Share and Cite MDPI and ACS Style Crudu, I.-A.; Arvinte, A.; Pinteala, M. Electrochemical Deposition of Silver—Gold Nanoparticles for Sensitive Dopamine Detection. Proceedings 2017, 1, 704. https://doi.org/10.3390/proceedings1080704 AMA Style Crudu I-A, Arvinte A, Pinteala M. Electrochemical Deposition of Silver—Gold Nanoparticles for Sensitive Dopamine Detection. Proceedings. 2017; 1(8):704. https://doi.org/10.3390/proceedings1080704 Chicago/Turabian Style Crudu, Irina-Alexandra, Adina Arvinte, and Mariana Pinteala. 2017. "Electrochemical Deposition of Silver—Gold Nanoparticles for Sensitive Dopamine Detection" Proceedings 1, no. 8: 704. https://doi.org/10.3390/proceedings1080704 Find Other Styles Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here. Article Metrics No No Article Access Statistics Multiple requests from the same IP address are counted as one view.