Abstract
In this study, we have successfully constructed a novel nano- micro structured octacalcium phosphate/protein composite coating on titanium by using an electrochemical deposition (ED) technique. The physico-chemical and biological properties of the coating were characterized by SEM, XRD, FT-IR, and in vivo test respectively. Under typical deposition conditions, the titanium surface formed a composite coating consisting of octacalcium phosphate and protein with a highly and hierarchically porous structure in nano-micro scale. This porous composite coating is similar to the natural bone structure. The preliminary in vivo evaluation demonstrates that the octacalcium phosphate/protein composite coating exhibits a preferable biocompatibility, and it is expected to become a new generational bone substitute materials.
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