Electrochemical Behavior of Unusual Dimeric Flavonoids Isolated from Fridericia platyphylla

Jessyane Rodrigues Do Nascimento ,Geyse Adriana Corrêa Ribeiro ,Iranaldo Santos Da Silva ,Roberto Alves De Lima ,Auro Atsushi Tanaka ,Sı́lvia Helena Pires Serrano ,Cláudia Quintino Da Rocha

doi:10.21577/0103-5053.20210031

Abstract

Brazil has the greatest plant diversity on the planet, distributed in different types of biomes. These plants are important sources of biologically active natural products, which are derived from various drugs marketed worldwide. This paper presents an electrochemical study of three unusual dimeric flavonoids, pharmacologically active, isolated and identified for the first time by our research group, in a Brazilian plant (Fridericia platyphylla). The results showed that oxidation processes are favored at higher pH, and mass transport was controlled by diffusion. Brachydins derivatives, Bra-A was oxidized at the lowest potential value (0.48 V vs. Ag/AgCl, KCl(sat)) and Bra-B and Bra-C, presented the highest oxidation potentials (ca. 0.71 and ca. 0.57 V vs. Ag/AgCl, KCl(sat), respectively). This study shows that electrochemistry is one more tool that would help us focus on future bio-pharmacological investigations of these unusual compounds.

Highlights

The Brazilian cerrado is one of the most biogeographically diverse regions in the world, containing numerous native species of vascular plants.[1,2] Many of these plants are commonly used in traditional medicine to treat various diseases.[2]
Flavonoids are natural products known for their noticeable antioxidant, anticancer, and anti-inflammatory activities.[9]
The present work aimed to investigate the electrochemical behaviors of the three unusual dimeric flavonoids isolated from Fridericia platyphylla

Summary

Introduction

The Brazilian cerrado (neotropical savannah) is one of the most biogeographically diverse regions in the world, containing numerous native species of vascular plants.[1,2] Many of these plants are commonly used in traditional medicine to treat various diseases.[2]. The present work aimed to investigate the electrochemical behaviors of the three unusual dimeric flavonoids isolated from Fridericia platyphylla.

Results

Conclusion