Electrocatalytic oxidation toward dopamine and acetaminophen based on AuNPs@TCnA/GN modified glassy carbon electrode

Abstract

In this paper, gold nanoparticles (AuNPs) modified by thiolated calix[n]arene (TCnA, n = 4, 6, 8) were anchored on graphene nanosheets (GN) by π-π stacking interaction between TCnA molecules and GN. Testing of various electrochemical techniques display that the AuNPs@TCnA/GN modified glass carbon electrodes (GCE) show good electrocatalytic property, molecular recognition and enrichment performance toward dopamine (DA) and acetaminophen (AC), and exhibit high current response. In all of modified electrodes, AuNPs@TC8A/GN/GCE shows an outstanding electrochemical response for DA and AC with high sensitivity of 5.08 and 9.76 mA mmol−1 L cm−2, respectively. The analytical curves for DA obtained by differential pulse voltammetry (DPV) are linear in the range from 0.5 to 150 μM and from 0.3 to 1.0 mM. The linear range for AC obtained by DPV is from 0.5 to 120 μM. Besides, AuNPs@TC8A/GN/GCE can be applied to determinate of DA and AC simultaneously, implying the prospect to develop a dual sensor under the same construction platform.