Abstract
A sensitive and selective electrochemical method for the determination of dopamine was developed using a p-nitrobenzenazo resorcinol (NBAR) polymer film modified glassy carbon electrode (GCE). The NBAR polymer film modified electrode shows excellent electrocatalytic activity toward the oxidation of dopamine (DA) in a phosphate buffer solution (pH 4.0). The linear range of 5.0 × 10 −6 to 2.5 × 10 −5 M and a detection limit of 3.0 × 10 −7 M were observed in pH 4.0 phosphate buffer solutions. The interference studies show that the modified electrode exhibits excellent selectivity in the presence of ascorbic acid (AA) and uric acid (UA) with a concentration respectively 30- and 3-times higher than that of DA, respectively. A remarkable improvement in cyclic voltammetric responses to DA, AA and UA (three well-defined voltammetric peaks at potentials around 0.390, 0.195 and 0.559 V for DA, AA and UA, respectively) and a noticeable enhancement of voltammetric sensitivity were observed at the NBAR polymer film modified GCE. This work provides a simple and easy approach to selective detection of dopamine in the presence of ascorbic acid and uric acid.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
